FNTA polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human FNTA.
Immunogen
Recombinant protein corresponding to human FNTA.
Sequence
LDSPSYVLYRHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)
Western Blot (1:100-250)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of (1) Human RT-4 cell, (2) Human U-251MG cell, (3) Human plasma (IgG/HSA depleted), (4) Human liver tissue, (5) Human tonsil tissue.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human prostate shows nuclear and cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of U-251 MG cell line with antibody shows positivity in cytosol (green). -
Gene Info — FNTA
Entrez GeneID
2339Protein Accession#
P49354Gene Name
FNTA
Gene Alias
FPTA, MGC99680, PGGT1A, PTAR2
Gene Description
farnesyltransferase, CAAX box, alpha
Omim ID
134635Gene Ontology
HyperlinkGene Summary
Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
FTase-alpha|GGTase-I-alpha|farnesyltransferase alpha-subunit|protein prenyltransferase alpha subunit repeat containing 2|ras proteins prenyltransferase alpha|type I protein geranyl-geranyltransferase alpha subunit
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Interactome
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Disease
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