PCDH18 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of (1) mouse liver, (2) rat liver.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PCDH18.
Immunogen
Recombinant protein corresponding to human PCDH18.
Sequence
IHKGDITLVPTINGTLPIRSHHRSSPSSSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVEQVSQLLSMLHQGQYQPRPSFRGNKYSRSYR
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
Western Blot (1:100-250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of (1) mouse liver, (2) rat liver.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. -
Gene Info — PCDH18
Entrez GeneID
54510Protein Accession#
Q9HCL0Gene Name
PCDH18
Gene Alias
DKFZp434B0923, KIAA1562, PCDH68L
Gene Description
protocadherin 18
Omim ID
608287Gene Ontology
HyperlinkGene Summary
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq
Other Designations
protocadherin 68-like protein
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Interactome
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Publication Reference
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Protocadherin-18 is a novel differentiation marker and an inhibitory signaling receptor for CD8+ effector memory T cells.
Vazquez-Cintron EJ, Monu NR, Burns JC, Blum R, Chen G, Lopez P, Ma J, Radoja S, Frey AB.
PLoS One 2012 May; 7(5):e36101.
Application：Flow Cyt, WB-Tr, Mouse, MCA38 cells.
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Protocadherin-18 is a novel differentiation marker and an inhibitory signaling receptor for CD8+ effector memory T cells.
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