CASC3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CASC3.
Immunogen
Recombinant protein corresponding to human CASC3.
Sequence
DAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with CASC3 polyclonal antibody (Cat # PAB31584) shows strong cytoplasmic positivity in seminiferous ducts. -
Gene Info — CASC3
Entrez GeneID
22794Protein Accession#
O15234Gene Name
CASC3
Gene Alias
BTZ, MLN51
Gene Description
cancer susceptibility candidate 3
Omim ID
606504Gene Ontology
HyperlinkGene Summary
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq
Other Designations
OTTHUMP00000164448|barentsz|metastatic lymph node 51
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