MORC1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human MORC1.
Immunogen
Recombinant protein corresponding to human MORC1.
Sequence
LSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:2500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with MORC1 polyclonal antibody (Cat # PAB31577) shows moderate nuclear positivity in cells in seminiferous ducts. -
Gene Info — MORC1
Entrez GeneID
27136Protein Accession#
Q86VD1Gene Name
MORC1
Gene Alias
MORC, ZCW6
Gene Description
MORC family CW-type zinc finger 1
Omim ID
603205Gene Ontology
HyperlinkGene Summary
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells. [provided by RefSeq
Other Designations
microrchidia homolog|microrchidia, mouse, homolog of|microrchidia, mouse, honolog of
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Interactome
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Disease
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