SLC2A2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC2A2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SLC2A2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of SLC2A2 polyclonal antibody (Cat # PAB3157) in HL-60 cell line lysates (35 ug/lane). SLC2A2 (arrow) was detected using the purified polyclonal antibody.Flow Cytometry
Flow cytometric analysis of HL-60 cells using SLC2A2 polyclonal antibody (Cat # PAB3157)(bottom histogram) compared to a negative control cell (top histogram).
FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
Gene Info — SLC2A2
Entrez GeneID
6514Protein Accession#
NP_000331;P11168Gene Name
SLC2A2
Gene Alias
GLUT2
Gene Description
solute carrier family 2 (facilitated glucose transporter), member 2
Gene Ontology
HyperlinkGene Summary
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Insulin but not phlorizin treatment induces a transient increase in GLUT2 gene expression in the kidney of diabetic rats.
Freitas HS, D'Agord Schaan B, da Silva RS, Okamoto MM, Oliveira-Souza M, Machado UF.
Nephron. Physiology 2007 Jan; 105(3):42.
Application:WB, Rat, Rat renal out-cortex.
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Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study.
Laukkanen O, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M.
Diabetes 2005 Jul; 54(7):2256.
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Expression of glucose transporter isoform GLUT-2 and glucokinase genes in human brain.
Roncero I, Alvarez E, Chowen JA, Sanz C, Rabano A, Vazquez P, Blazquez E.
Journal of Neurochemistry 2004 Mar; 88(5):1203.
Application:WB, Human, Rat, HepG2 cells, Human brains, Rat livers.
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Insulin but not phlorizin treatment induces a transient increase in GLUT2 gene expression in the kidney of diabetic rats.
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