KRT75 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human hair with KRT75 polyclonal antibody (Cat # PAB31530) shows strong cytoplasmic positivity in cells in external root sheath.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human KRT75.
Immunogen
Recombinant protein corresponding to human KRT75.
Sequence
MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human hair with KRT75 polyclonal antibody (Cat # PAB31530) shows strong cytoplasmic positivity in cells in external root sheath. -
Gene Info — KRT75
Entrez GeneID
9119Protein Accession#
O95678Gene Name
KRT75
Gene Alias
K6HF, KB18, PFB
Gene Description
keratin 75
Omim ID
609025Gene Ontology
HyperlinkGene Summary
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). [provided by RefSeq
Other Designations
cytokeratin type II|cytokeratin-75|keratin-6 hair follicle|type II keratin-18
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