CAPG polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CAPG.
Immunogen
Recombinant protein corresponding to human CAPG.
Sequence
ERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVAD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with CAPG polyclonal antibody (Cat # PAB31527) shows strong cytoplasmic and nuclear positivity in macrophages. -
Gene Info — CAPG
Entrez GeneID
822Protein Accession#
P40121Gene Name
CAPG
Gene Alias
AFCP, MCP
Gene Description
capping protein (actin filament), gelsolin-like
Omim ID
153615Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq
Other Designations
actin-regulatory protein CAP-G|gelsolin-like capping protein|macrophage capping protein
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Interactomes
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Diseases
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