ABCC12 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human ABCC12.
Immunogen
Recombinant protein corresponding to human ABCC12.
Sequence
GPYLISDLDQRGRRRSFAERYDPSLKTMIPVRPCARLAPNPVDDAGLLSFATFSWLTPVMVKGYRQRLTVDTLPPLSTYDSSDTNAKRFRV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach, upper with ABCC12 polyclonal antibody (Cat # PAB31498) shows strong cytoplasmic positivity in glandular cells. -
Gene Info — ABCC12
Entrez GeneID
94160Protein Accession#
Q96J65Gene Name
ABCC12
Gene Alias
MGC27071, MRP9
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Omim ID
607041Gene Ontology
HyperlinkGene Summary
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq
Other Designations
ATP-binding cassette protein C12|ATP-binding cassette transporter sub-family C member 12|OTTHUMP00000164186|multidrug resistance-associated protein 9
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Pathway
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Disease
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