CDC16 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: RT-4 and Lane 2: U-251 MG sp cell lysates with CDC16 polyclonal antibody (Cat # PAB31494).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with CDC16 polyclonal antibody (Cat # PAB31494) shows strong cytoplasmic positivity in cells in tubules.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CDC16.
Immunogen
Recombinant protein corresponding to human CDC16.
Sequence
KDKLKCYDFDVHTMKTLKNIISPPWDFREFEVEKQTAEETGLTPLETSRKTPDSRPSLEETFEIEMNESDMMLETSMSDHST
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:2500-1:5000)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: RT-4 and Lane 2: U-251 MG sp cell lysates with CDC16 polyclonal antibody (Cat # PAB31494).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with CDC16 polyclonal antibody (Cat # PAB31494) shows strong cytoplasmic positivity in cells in tubules. -
Gene Info — CDC16
Entrez GeneID
8881Protein Accession#
Q13042Gene Name
CDC16
Gene Alias
APC6
Gene Description
cell division cycle 16 homolog (S. cerevisiae)
Omim ID
603461Gene Ontology
HyperlinkGene Summary
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
anaphase-promoting complex, subunit 6
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Interactome
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Pathway
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Disease
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