CYBRD1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CYBRD1.
Immunogen
Recombinant protein corresponding to human CYBRD1.
Sequence
VTRPQWKRPKEPNSTILHPNGGTEQGARGSMPAYSGNNMDKSDSELNNEVAARKRNLALDEAGQRSTM
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: RT-4 and Lane 2: U-251 MG sp cell lysates with CYBRD1 polyclonal antibody (Cat # PAB31449).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon with CYBRD1 polyclonal antibody (Cat # PAB31449) shows strong cytoplasmic and membranous positivity in glandular cells. -
Gene Info — CYBRD1
Entrez GeneID
79901Protein Accession#
Q53TN4Gene Name
CYBRD1
Gene Alias
DCYTB, FLJ23462, FRRS3
Gene Description
cytochrome b reductase 1
Omim ID
605745Gene Ontology
HyperlinkGene Summary
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq
Other Designations
duodenal cytochrome b|ferric-chelate reductase 3
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Interactome
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Disease
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Publication Reference
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DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms.
Lemler DJ, Lynch ML, Tesfay L, Deng Z, Paul BT, Wang X, Hegde P, Manz DH, Torti SV, Torti FM.
Breast Cancer Research 2017 Mar; 19(1):25.
Application:IF, IHC, WB-Tr, Human, Human breast tissue microarray, T-47D, MCF-7, SK-BR-3 cells.
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DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms.
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