LXN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human LXN.
Immunogen
Recombinant protein corresponding to human LXN.
Sequence
MEIPPTNYPASRAALVAQNYINYQQGTPHRVFEVQKVKQASMEDIPGRGHKYHLKFAVEEIIQKQVKVNCTAEVLYPSTGQETAPEVNFTFEGETGKNPDEEDNTF
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: NIH-3T3 cell lysate (mouse embryonic fibroblast cells) and Lane 2: NBT-II cell lysate (Wistar rat bladder tumour cells) with LXN polyclonal antibody (Cat # PAB31443).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with LXN polyclonal antibody (Cat # PAB31443) shows strong cytoplasmic and nuclear positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of MCF7 cells with LXN polyclonal antibody (Cat # PAB31443) (Green) shows localization to nucleoplasm and cytosol. -
Gene Info — LXN
Entrez GeneID
56925Protein Accession#
Q9BS40Gene Name
LXN
Gene Alias
ECI, TCI
Gene Description
latexin
Omim ID
609305Gene Ontology
HyperlinkGene Summary
This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. [provided by RefSeq
Other Designations
endogenous carboxypeptidase inhibitor
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Interactome
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Publication Reference
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The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.
Muthusamy V, Premi S, Soper C, Platt J, Bosenberg M.
The Journal of Investigative Dermatology 2013 Jul; 133(7):1827.
Application:IHC-Fr, WB-Ce, WB-Ti, WB-Tr, Human, C8161 cells, Human malignant melanoma, Human melanoma cell lines.
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The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.
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