CYP4F2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with CYP4F2 polyclonal antibody (Cat # PAB31441) shows moderate cytoplasmic positivity in hepatocytes.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CYP4F2.
Immunogen
Recombinant protein corresponding to human CYP4F2.
Sequence
RRNWFWGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with CYP4F2 polyclonal antibody (Cat # PAB31441) shows moderate cytoplasmic positivity in hepatocytes. -
Gene Info — CYP4F2
Entrez GeneID
8529Protein Accession#
P78329Gene Name
CYP4F2
Gene Alias
CPF2
Gene Description
cytochrome P450, family 4, subfamily F, polypeptide 2
Omim ID
604426Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away. [provided by RefSeq
Other Designations
cytochrome P450, subfamily IVF, polypeptide 2|leukotriene B4 omega-hydroxylase|leukotriene-B4 20-monooxygenase
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Interactome
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Pathway
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Disease
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Publication Reference
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20-HETE-producing enzymes are up-regulated in human cancers.
Alexanian A, Miller B, Roman RJ, Sorokin A.
Cancer Genomics & Proteomics 2012 Jul; 94:163.
Application：WB-Ti, Human, Ovary.
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20-HETE-producing enzymes are up-regulated in human cancers.
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