XCR1 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: negative control (vector only transfected HEK293T cell lysate) and Lane 2: over-expression lysate (co-expressed with a C-terminal myc-DDK tag in mammalian HEK293T cells) with XCR1 polyclonal antibody (Cat # PAB31438).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with XCR1 polyclonal antibody (Cat # PAB31438) shows strong cytoplasmic positivity in macrophages.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human XCR1.
Immunogen
Recombinant protein corresponding to human XCR1.
Sequence
MESSGNPESTTFFYYDLQSQPCENQAWVFATLA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: negative control (vector only transfected HEK293T cell lysate) and Lane 2: over-expression lysate (co-expressed with a C-terminal myc-DDK tag in mammalian HEK293T cells) with XCR1 polyclonal antibody (Cat # PAB31438).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with XCR1 polyclonal antibody (Cat # PAB31438) shows strong cytoplasmic positivity in macrophages. -
Gene Info — XCR1
Entrez GeneID
2829Protein Accession#
P46094Gene Name
XCR1
Gene Alias
CCXCR1, GPR5
Gene Description
chemokine (C motif) receptor 1
Omim ID
600552Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
G protein-coupled receptor 5|XC chemokine receptor 1|chemokine (C motif) XC receptor 1|lymphotactin receptor
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Interactome
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Pathway
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Disease
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