CES1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with CES1 polyclonal antibody (Cat # PAB31431).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with CES1 polyclonal antibody (Cat # PAB31431) shows strong cytoplasmic positivity in hepatocytes.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CES1.
Immunogen
Recombinant protein corresponding to human CES1.
Sequence
VTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with CES1 polyclonal antibody (Cat # PAB31431).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with CES1 polyclonal antibody (Cat # PAB31431) shows strong cytoplasmic positivity in hepatocytes. -
Gene Info — CES1
Entrez GeneID
1066Protein Accession#
P23141Gene Name
CES1
Gene Alias
ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH
Gene Description
carboxylesterase 1 (monocyte/macrophage serine esterase 1)
Omim ID
114835Gene Ontology
HyperlinkGene Summary
Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
acyl coenzyme A:cholesterol acyltransferase|carboxylesterase 1|carboxylesterase 2 (liver)|cholesteryl ester hydrolase|egasyn|liver carboxylesterase|triacylglycerol hydrolase
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Interactome
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Pathway
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Disease
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