FCER2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human FCER2.
Immunogen
Recombinant protein corresponding to human FCER2.
Sequence
VHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: negative control (vector only transfected HEK293T cell lysate) and Lane 2: over-expression lysate (co-expressed with a C-terminal myc-DDK tag in mammalian HEK293T cells) with FCER2 polyclonal antibody (Cat # PAB31411).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with FCER2 polyclonal antibody (Cat # PAB31411) shows strong cytoplasmic positivity in reaction center cells. -
Gene Info — FCER2
Entrez GeneID
2208Protein Accession#
P06734Gene Name
FCER2
Gene Alias
CD23, CD23A, CLEC4J, FCE2, IGEBF
Gene Description
Fc fragment of IgE, low affinity II, receptor for (CD23)
Omim ID
151445Gene Ontology
HyperlinkGene Summary
The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.[supplied by OMIM
Other Designations
C-type lectin domain family 4, member J|CD23 antigen|Fc fragment of IgE, low affinity II, receptor for (CD23A)
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Interactome
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Pathway
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Disease
- Asthma
- Birth Weight
- Bronchiolitis
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Infant
- Leukemia
- Lung Neoplasms
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