PPBP polyclonal antibody
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell, Lane 3: human plasma tissue (IgG/HSA depleted) and Lane 4: human liver tissue lysates with PPBP polyclonal antibody (Cat # PAB31401).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bone marrow with PPBP polyclonal antibody (Cat # PAB31401) shows strong cytoplasmic positivity in megakaryocytes of bone marrow poietic cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PPBP.
Immunogen
Recombinant protein corresponding to human PPBP.
Sequence
GQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell, Lane 3: human plasma tissue (IgG/HSA depleted) and Lane 4: human liver tissue lysates with PPBP polyclonal antibody (Cat # PAB31401).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bone marrow with PPBP polyclonal antibody (Cat # PAB31401) shows strong cytoplasmic positivity in megakaryocytes of bone marrow poietic cells. -
Gene Info — PPBP
Entrez GeneID
5473Protein Accession#
P02775Gene Name
PPBP
Gene Alias
B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1
Gene Description
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
Omim ID
121010Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. [provided by RefSeq
Other Designations
CXC chemokine ligand 7|beta-thromboglobulin|connective tissue-activating peptide III|leukocyte-derived growth factor|low-affinity platelet factor IV|macrophage-derived growth factor|neutrophil-activating peptide 2|neutrophil-activating peptide-2|platelet
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Interactome
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Pathway
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Disease
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Publication Reference
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Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model.
Kato BS, Nicholson G, Neiman M, Rantalainen M, Holmes CC, Barrett A, Uhlén M, Nilsson P, Spector TD, Schwenk JM.
Proteome Science 2011 Nov; 9:73.
Application：Array, Recombinant protein.
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Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model.
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