SCTR polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SCTR.
Immunogen
Recombinant protein corresponding to human SCTR.
Sequence
CDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with SCTR polyclonal antibody (Cat # PAB31386) shows strong cytoplasmic and membranous positivity in epidermal cells. -
Gene Info — SCTR
Entrez GeneID
6344Protein Accession#
P47872Gene Name
SCTR
Gene Alias
SR
Gene Description
secretin receptor
Omim ID
182098Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq
Other Designations
pancreatic secretin receptor
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Interactome
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Pathway
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Publication Reference
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Combination of secretin and fluvastatin ameliorates the polyuria associated with X-linked nephrogenic diabetes insipidus in mice.
Procino G, Milano S, Carmosino M, Barbieri C, Nicoletti MC, H. Li J, Wess J, Svelto M.
Kidney International 2014 Jul; 86(1):127.
Application:IF, IHC-Fr, WB-Ti, Human, Mouse, Human kidney, Mouse kidney.
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Combination of secretin and fluvastatin ameliorates the polyuria associated with X-linked nephrogenic diabetes insipidus in mice.
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