ZMPSTE24 polyclonal antibody
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell and Lane 3: human plasma tissue (IgG/HSA depleted) lysates with ZMPSTE24 polyclonal antibody (Cat # PAB31382).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with ZMPSTE24 polyclonal antibody (Cat # PAB31382) shows strong cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human ZMPSTE24.
Immunogen
Recombinant protein corresponding to human ZMPSTE24.
Sequence
KTTTHVPPELGQIMDSETFEKSRLYQLDKSTFS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell and Lane 3: human plasma tissue (IgG/HSA depleted) lysates with ZMPSTE24 polyclonal antibody (Cat # PAB31382).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with ZMPSTE24 polyclonal antibody (Cat # PAB31382) shows strong cytoplasmic positivity in glandular cells. -
Gene Info — ZMPSTE24
Entrez GeneID
10269Protein Accession#
O75844Gene Name
ZMPSTE24
Gene Alias
FACE-1, FACE1, FLJ14968, STE24, Ste24p
Gene Description
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq
Other Designations
CAAX prenyl protease|OTTHUMP00000006394|farnesylated-proteins converting enzyme 1|prenyl protein-specific endoprotease 1|zinc metalloproteinase STE24
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Interactome
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Disease
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