PRDX6 polyclonal antibody
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell, Lane 3: human plasma tissue (IgG/HSA depleted), Lane 4: human liver tissue and Lane 5: human tonsil tissue lysates with PRDX6 polyclonal antibody (Cat # PAB31381).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with PRDX6 polyclonal antibody (Cat # PAB31381) shows strong nuclear and cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PRDX6.
Immunogen
Recombinant protein corresponding to human PRDX6.
Sequence
GGLLLGDVAPNFEANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFVFGPDKKLKLSILYPA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell, Lane 3: human plasma tissue (IgG/HSA depleted), Lane 4: human liver tissue and Lane 5: human tonsil tissue lysates with PRDX6 polyclonal antibody (Cat # PAB31381).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with PRDX6 polyclonal antibody (Cat # PAB31381) shows strong nuclear and cytoplasmic positivity in glandular cells. -
Gene Info — PRDX6
Entrez GeneID
9588Protein Accession#
P30041Gene Name
PRDX6
Gene Alias
1-Cys, AOP2, KIAA0106, MGC46173, NSGPx, PRX, aiPLA2, p29
Gene Description
peroxiredoxin 6
Omim ID
602316Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq
Other Designations
1-Cys peroxiredoxin|OTTHUMP00000032693|acidic calcium-independent phospholipase A2|antioxidant protein 2|non-selenium glutathione peroxidase
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Interactome
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Pathway
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Disease
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Publication Reference
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Human Protein Atlas of redox systems - what can be learnt?
Dammeyer P, Arnér ES.
Biochimica et Biophysica Acta 2011 Jan; 1810(1):111.
Application：IHC, Human, Human breast, Human kidney, Human liver, Human lung, Human ovary, Human testes.
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Human Protein Atlas of redox systems - what can be learnt?
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