BIRC2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: RT-4 and Lane 2: U-251 MG sp cell lysates with BIRC2 polyclonal antibody (Cat # PAB31364).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with BIRC2 polyclonal antibody (Cat # PAB31364) shows moderate cytoplasmic positivity in cells in tubules.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human BIRC2.
Immunogen
Recombinant protein corresponding to human BIRC2.
Sequence
NWKLGDSPIQKHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGF
Host
Rabbit
Reactivity
Human, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: RT-4 and Lane 2: U-251 MG sp cell lysates with BIRC2 polyclonal antibody (Cat # PAB31364).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with BIRC2 polyclonal antibody (Cat # PAB31364) shows moderate cytoplasmic positivity in cells in tubules. -
Gene Info — BIRC2
Entrez GeneID
329Protein Accession#
Q13490Gene Name
BIRC2
Gene Alias
API1, HIAP2, Hiap-2, MIHB, RNF48, cIAP1
Gene Description
baculoviral IAP repeat-containing 2
Omim ID
601712Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq
Other Designations
NFR2-TRAF signalling complex protein|apoptosis inhibitor 1|baculoviral IAP repeat-containing protein 2
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Interactome
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Pathway
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Disease
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