IL17RB polyclonal antibody
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell, Lane 3: human plasma tissue (IgG/HSA depleted) and Lane 4: human liver tissue lysates with IL17RB polyclonal antibody (Cat # PAB31362).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with IL17RB polyclonal antibody (Cat # PAB31362) shows strong cytoplasmic positivity in tubular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human IL17RB.
Immunogen
Recombinant protein corresponding to human IL17RB.
Sequence
QCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: RT-4 cell, Lane 2: U-251 MG sp cell, Lane 3: human plasma tissue (IgG/HSA depleted) and Lane 4: human liver tissue lysates with IL17RB polyclonal antibody (Cat # PAB31362).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with IL17RB polyclonal antibody (Cat # PAB31362) shows strong cytoplasmic positivity in tubular cells. -
Gene Info — IL17RB
Entrez GeneID
55540Protein Accession#
Q9NRM6Gene Name
IL17RB
Gene Alias
CRL4, EVI27, IL17BR, IL17RH1, MGC5245
Gene Description
interleukin 17 receptor B
Omim ID
605458Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq
Other Designations
IL-17B receptor|cytokine receptor CRL4|interleukin 17 receptor homolog 1|interleukin 17B receptor
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Interactome
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Pathway
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Disease
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