PTGDS polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: negative control (vector only transfected HEK293T cell lysate) and Lane 2: over-expression lysate (co-expressed with a C-terminal myc-DDK tag in mammalian HEK293T cells) with PTGDS polyclonal antibody (Cat # PAB31353).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lateral ventricle with PTGDS polyclonal antibody (Cat # PAB31353) shows strong cytoplasmic positivity in granular pattern in glial and neuronal cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PTGDS.
Immunogen
Recombinant protein corresponding to human PTGDS.
Sequence
SWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: negative control (vector only transfected HEK293T cell lysate) and Lane 2: over-expression lysate (co-expressed with a C-terminal myc-DDK tag in mammalian HEK293T cells) with PTGDS polyclonal antibody (Cat # PAB31353).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lateral ventricle with PTGDS polyclonal antibody (Cat # PAB31353) shows strong cytoplasmic positivity in granular pattern in glial and neuronal cells. -
Gene Info — PTGDS
Entrez GeneID
5730Protein Accession#
P41222Gene Name
PTGDS
Gene Alias
LPGDS, PDS, PGD2, PGDS, PGDS2
Gene Description
prostaglandin D2 synthase 21kDa (brain)
Omim ID
176803Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq
Other Designations
OTTHUMP00000022638|PGD2 synthase|beta-trace protein|glutathione-independent PGD synthase|lipocalin-type prostaglandin D synthase|prostaglandin D synthase|prostaglandin D2 synthase (21kD, brain)|prostaglandin H2 D-isomerase|prostaglandin-H2 D-isomerase
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Interactome
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Pathway
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Disease
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