NNT polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of RH-30 cell lysate with NNT polyclonal antibody (Cat # PAB31342).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with NNT polyclonal antibody (Cat # PAB31342) shows strong cytoplasmic positivity in cells in tubules.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human NNT.
Immunogen
Recombinant protein corresponding to human NNT.
Sequence
ANLLKTVVTGCSCPLLSNLGSCKGLRVKKDFLRTFYTHQELWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQNLVKQGFNVVVESGAGEASKFSDDHYRVAGAQIQGAKEVLASDLVVKVRAPMVNPTLGVHEADLLKTSGT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of RH-30 cell lysate with NNT polyclonal antibody (Cat # PAB31342).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with NNT polyclonal antibody (Cat # PAB31342) shows strong cytoplasmic positivity in cells in tubules. -
Gene Info — NNT
Entrez GeneID
23530Protein Accession#
Q13423Gene Name
NNT
Gene Alias
MGC126502, MGC126503
Gene Description
nicotinamide nucleotide transhydrogenase
Omim ID
607878Gene Ontology
HyperlinkGene Summary
This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq
Other Designations
NAD(P) transhydrogenase|OTTHUMP00000122433|pyridine nucleotide transhydrogenase
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Interactome
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Pathway
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