MRC2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human MRC2.
Immunogen
Recombinant protein corresponding to human MRC2.
Sequence
EEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human small intestine with MRC2 polyclonal antibody (Cat # PAB31250) shows moderate cytoplasmic positivity in glandular cells. -
Gene Info — MRC2
Entrez GeneID
9902Protein Accession#
Q9UBG0Gene Name
MRC2
Gene Alias
CD280, CLEC13E, ENDO180, FLJ35911, KIAA0709, UPARAP
Gene Description
mannose receptor, C type 2
Gene Ontology
HyperlinkGene Summary
MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation (Wienke et al., 2007 [PubMed 17974964]).[supplied by OMIM
Other Designations
endocytic receptor (macrophage mannose receptor family)|urokinase plasminogen activator receptor-associated protein
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Interactome
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Disease
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