MARK2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon with MARK2 polyclonal antibody (Cat # PAB31221) shows strong cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human MARK2.
Immunogen
Recombinant protein corresponding to human MARK2.
Sequence
SIFSKFTSKFVRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon with MARK2 polyclonal antibody (Cat # PAB31221) shows strong cytoplasmic positivity in glandular cells. -
Gene Info — MARK2
Entrez GeneID
2011Protein Accession#
Q7KZI7Gene Name
MARK2
Gene Alias
EMK1, MGC99619, PAR-1, Par1b
Gene Description
MAP/microtubule affinity-regulating kinase 2
Omim ID
600526Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ELKL motif kinase 1|Ser/Thr protein kinase PAR-1B|protein-serine/threonine kinase|serine/threonine kinase
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Interactome
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Disease
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