ANAPC4 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with ANAPC4 polyclonal antibody (Cat # PAB31215) shows strong cytoplasmic and nuclear positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human ANAPC4.
Immunogen
Recombinant protein corresponding to human ANAPC4.
Sequence
VTVVLKDTVGREGRDRLLVQLPLSLVYNSEDSAEYQFTGTYSTRLDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with ANAPC4 polyclonal antibody (Cat # PAB31215) shows strong cytoplasmic and nuclear positivity in glandular cells. -
Gene Info — ANAPC4
Entrez GeneID
29945Protein Accession#
Q9UJX5Gene Name
ANAPC4
Gene Alias
APC4
Gene Description
anaphase promoting complex subunit 4
Omim ID
606947Gene Ontology
HyperlinkGene Summary
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. [provided by RefSeq
Other Designations
anaphase-promoting complex subunit 4
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Interactome
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Pathway
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