SNX6 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SNX6.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SNX6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of SNX6 polyclonal antibody (Cat # PAB3121) in HepG2 cell line lysates (35 ug/lane). SNX6 (arrow) was detected using the purified polyclonal antibody. -
Gene Info — SNX6
Entrez GeneID
58533Protein Accession#
NP_689419;Q9UNH7Gene Name
SNX6
Gene Alias
MGC3157, MSTP010, TFAF2
Gene Description
sorting nexin 6
Omim ID
606098Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000178808|OTTHUMP00000178809|tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2
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Interactome
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Publication Reference
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Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases.
Parks WT, Frank DB, Huff C, Renfrew Haft C, Martin J, Meng X, de Caestecker MP, McNally JG, Reddi A, Taylor SI, Roberts AB, Wang T, Lechleider RJ.
The Journal of Biological Chemistry 2001 Jun; 276(22):19332.
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Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases.
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