CCR4 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with CCR4 polyclonal antibody (Cat # PAB31174) shows moderate to strong cytoplasmic positivity in a subset of lymphoid cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CCR4.
Immunogen
Recombinant protein corresponding to human CCR4.
Sequence
LQIYSADTPSSSYTQSTMDHDLHDAL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with CCR4 polyclonal antibody (Cat # PAB31174) shows moderate to strong cytoplasmic positivity in a subset of lymphoid cells. -
Gene Info — CCR4
Entrez GeneID
1233Protein Accession#
P51679Gene Name
CCR4
Gene Alias
CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293
Gene Description
chemokine (C-C motif) receptor 4
Omim ID
604836Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq
Other Designations
chemokine (C-C) receptor 4
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Interactome
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Pathway
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Disease
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