MCL1 polyclonal antibody

Catalog # PAB31161

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with MCL1 polyclonal antibody (Cat # PAB31161) shows strong cytoplasmic positivity(granular pattern) in parietal cells.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against partial recombinant human MCL1.

    Immunogen

    Recombinant protein corresponding to human MCL1.

    Sequence

    MLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with MCL1 polyclonal antibody (Cat # PAB31161) shows strong cytoplasmic positivity(granular pattern) in parietal cells.
  • Gene Info — MCL1

    Entrez GeneID

    4170

    Protein Accession#

    Q07820

    Gene Name

    MCL1

    Gene Alias

    BCL2L3, EAT, MCL1L, MCL1S, MGC104264, MGC1839, TM

    Gene Description

    myeloid cell leukemia sequence 1 (BCL2-related)

    Omim ID

    159552

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. [provided by RefSeq

    Other Designations

    OTTHUMP00000032794|OTTHUMP00000032795|induced myeloid leukemia cell differentiation protein Mcl-1|myeloid cell leukemia sequence 1|myeloid cell leukemia sequence 1, isoform 1

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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