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Last updated: 2017/9/17

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MCL1 polyclonal antibody

  • Catalog # : PAB31161
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant human MCL1.
  • Immunogen:
  • Recombinant protein corresponding to human MCL1.
  • Sequence:
  • MLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with MCL1 polyclonal antibody (Cat # PAB31161) shows strong cytoplasmic positivity(granular pattern) in parietal cells.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4170
  • Gene Name:
  • MCL1
  • Gene Alias:
  • BCL2L3,EAT,MCL1L,MCL1S,MGC104264,MGC1839,TM
  • Gene Description:
  • myeloid cell leukemia sequence 1 (BCL2-related)
  • Gene Summary:
  • The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032794,OTTHUMP00000032795,induced myeloid leukemia cell differentiation protein Mcl-1,myeloid cell leukemia sequence 1,myeloid cell leukemia sequence 1, isoform 1
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