SEMA3A polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with SEMA3A polyclonal antibody (Cat # PAB31132) shows cytoplasmic positivity in hepatocytes.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SEMA3A.
Immunogen
Recombinant protein corresponding to human SEMA3A.
Sequence
VPRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with SEMA3A polyclonal antibody (Cat # PAB31132) shows cytoplasmic positivity in hepatocytes. -
Gene Info — SEMA3A
Entrez GeneID
10371Protein Accession#
Q14563Gene Name
SEMA3A
Gene Alias
Hsema-I, Hsema-III, MGC133243, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1
Gene Description
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Omim ID
603961Gene Ontology
HyperlinkGene Summary
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq
Other Designations
collapsin 1|semaphorin 3A|semaphorin D|semaphorin III|semaphorin L|semaphorin-like
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Interactome
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Pathway
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Disease
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