FZD7 polyclonal antibody

Catalog # PAB31107

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunofluorescence
Application

Immunofluorescence

Immunofluorescent staining of CACO-2 cell line with antibody shows positivity in nucleoplasma (green).

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against partial recombinant human FZD7.

    Immunogen

    Recombinant protein corresponding to human FZD7.

    Sequence

    CVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTAL

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunofluorescence

    Immunofluorescent staining of CACO-2 cell line with antibody shows positivity in nucleoplasma (green).
  • Gene Info — FZD7

    Entrez GeneID

    8324

    Protein Accession#

    O75084

    Gene Name

    FZD7

    Gene Alias

    FzE3

    Gene Description

    frizzled homolog 7 (Drosophila)

    Omim ID

    603410

    Gene Ontology

    Hyperlink

    Gene Summary

    Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq

    Other Designations

    Frizzled, drosophila, homolog of, 7|frizzled 7

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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