DVL2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of (1) Human RT-4 cell, (2) Human U-251MG sp cell.
Immunofluorescence
Immunofluorescent staining of SH-SY5Y cell line with antibody shows positivity in nucleoplasma (green).
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human DVL2.
Immunogen
Recombinant protein corresponding to human DVL2.
Sequence
PNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:100-250)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of (1) Human RT-4 cell, (2) Human U-251MG sp cell.Immunofluorescence
Immunofluorescent staining of SH-SY5Y cell line with antibody shows positivity in nucleoplasma (green). -
Gene Info — DVL2
Entrez GeneID
1856Protein Accession#
O14641Gene Name
DVL2
Gene Alias
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Gene Description
dishevelled, dsh homolog 2 (Drosophila)
Omim ID
602151Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq
Other Designations
DSH homolog 2|dishevelled 2|dishevelled 2 (homologous to Drosophila dsh)|segment polarity protein dishevelled homolog DVL-2
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Interactome
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Pathway
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Disease
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