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Last updated: 2016/12/4
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EPM2A polyclonal antibody

  • Catalog # : PAB3106
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of EPM2A.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human EPM2A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:10-50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of EPM2A (arrow) using rabbit EPM2A polyclonal antibody (Cat # PAB3106). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EPM2A gene (Lane 2) (Origene Technologies).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with EPM2A polyclonal antibody (Cat # PAB3106) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7957
  • Protein Accession#:
  • NP_005661;O95278
  • Gene Name:
  • EPM2A
  • Gene Alias:
  • EPM2,MELF
  • Gene Description:
  • epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
  • Gene Summary:
  • This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017360,epilepsy, progressive myoclonus type 2, Lafora disease (laforin),laforin
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