PLD1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PLD1.
Immunogen
Recombinant protein corresponding to human PLD1.
Sequence
NEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human gallbladder shows strong membranous and cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of U-2 OS cell line with antibody shows positivity in plasma membrane (green). -
Gene Info — PLD1
Entrez GeneID
5337Protein Accession#
Q13393Gene Name
PLD1
Gene Alias
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Gene Description
phospholipase D1, phosphatidylcholine-specific
Omim ID
602382Gene Ontology
HyperlinkGene Summary
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995 [PubMed 8530346]).[supplied by OMIM
Other Designations
choline phosphatase 1|phospholipase D1, phophatidylcholine-specific
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Interactome
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