THBD polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human THBD.
Immunogen
Recombinant protein corresponding to human THBD.
Sequence
DVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITYG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human lung tissue lysate with THBD polyclonal antibody (Cat # PAB31005).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with THBD polyclonal antibody (Cat # PAB31005) shows strong membranous positivity in trophoblastic cells. -
Gene Info — THBD
Entrez GeneID
7056Protein Accession#
P07204Gene Name
THBD
Gene Alias
CD141, THRM, TM
Gene Description
thrombomodulin
Omim ID
188040Gene Ontology
HyperlinkGene Summary
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq
Other Designations
CD141 antigen|OTTHUMP00000030415|fetomodulin
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Interactome
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