UBXN11 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human UBXN11.
Immunogen
Recombinant protein corresponding to human UBXN11.
Sequence
SENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with UBXN11 polyclonal antibody (Cat # PAB30994) shows strong cytoplasmic positivity in exocrine cells. -
Gene Info — UBXN11
Entrez GeneID
91544Protein Accession#
Q5T124Gene Name
UBXN11
Gene Alias
COA-1, DKFZp686F04228, PP2243, SOC, SOCI, UBXD5
Gene Description
UBX domain protein 11
Omim ID
609151Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000003460|OTTHUMP00000003461|OTTHUMP00000003462|OTTHUMP00000003463|UBX domain containing 5|colorectal tumor-associated antigen-1|socius
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