THEM4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human THEM4.
Immunogen
Recombinant protein corresponding to human THEM4.
Sequence
PPGFIHGGAIATMIDATVGMCAMMAGGIVMTANLNINYKRPIPLCSVVMINSQLDKVEGRKFFVSCNVQSVDEKTLYSEATSLFIKLNPAKSL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with THEM4 polyclonal antibody (Cat # PAB30987) shows strong cytoplasmic positivity in exocrine glandular cells. -
Gene Info — THEM4
Entrez GeneID
117145Protein Accession#
Q5T1C6Gene Name
THEM4
Gene Alias
CTMP, MGC29636
Gene Description
thioesterase superfamily member 4
Omim ID
606388Gene Ontology
HyperlinkGene Summary
Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq
Other Designations
C-terminal modulator protein|OTTHUMP00000015248
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