ITGB3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human ITGB3.
Immunogen
Recombinant protein corresponding to human ITGB3.
Sequence
VRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bone marrow with ITGB3 polyclonal antibody (Cat # PAB30984) shows strong cytoplasmic positivity in megakaryocytes. -
Gene Info — ITGB3
Entrez GeneID
3690Protein Accession#
P05106Gene Name
ITGB3
Gene Alias
CD61, GP3A, GPIIIa
Gene Description
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Omim ID
173470Gene Ontology
HyperlinkGene Summary
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq
Other Designations
integrin beta chain, beta 3|platelet glycoprotein IIIa
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Interactome
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Disease
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