Western blot analysis of STK39 polyclonal antibody (Cat # PAB3097) in mouse liver tissue lysates (35 ug/lane). STK39 (arrow) was detected using the purified polyclonal antibody.
Western Blot (Transfected lysate)
Western blot analysis of STK39 (arrow) using rabbit STK39 polyclonal antibody (Cat # PAB3097). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the STK39 gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with STK39 polyclonal antibody (Cat # PAB3097) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq
Ste20-like protein kinase,proline-alanine-rich STE20-related kinase,small intestine SPAK-like kinase