CRNN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CRNN.
Immunogen
Recombinant protein corresponding to human CRNN.
Sequence
YDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human oral mucosa with CRNN polyclonal antibody (Cat # PAB30949) shows strong cytoplasmic positivity in squamous epithelial cells. -
Gene Info — CRNN
Entrez GeneID
49860Protein Accession#
Q9UBG3Gene Name
CRNN
Gene Alias
C1orf10, DRC1, PDRC1, SEP53
Gene Description
cornulin
Omim ID
611312Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq
Other Designations
53 kDa squamous epithelial-induced stress protein|OTTHUMP00000014323|squamous epithelial heat shock protein 53|tumor-related protein
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Interactome
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Disease
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