PLG polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PLG.
Immunogen
Recombinant protein corresponding to human PLG.
Sequence
NKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon with PLG polyclonal antibody (Cat # PAB30924) shows positivity in plasma. -
Gene Info — PLG
Entrez GeneID
5340Protein Accession#
P00747Gene Name
PLG
Gene Alias
DKFZp779M0222
Gene Description
plasminogen
Gene Ontology
HyperlinkGene Summary
Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU; MIM 191840) and tissue plasminogen activator (PLAT; MIM 173370). The main function of plasmin is to dissolve fibrin (see, e.g., FGA, MIM 134820) clots. Plasmin, like trypsin, belongs to the family of serine proteinases (Miyata et al., 1982 [PubMed 6216475]; Forsgren et al., 1987 [PubMed 3030813]).[supplied by OMIM
Other Designations
OTTHUMP00000017544
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Interactome
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Pathway
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Disease
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Publication Reference
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Subunits of the Pyruvate Dehydrogenase Cluster of Mycoplasma pneumoniae Are Surface-Displayed Proteins that Bind and Activate Human Plasminogen.
Gründel A, Friedrich K, Pfeiffer M, Jacobs E, Dumke R.
PLoS One 2015 May; 10(5):e0126600.
Application:ELISA, WB-Re, Recombinant protein.
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Subunits of the Pyruvate Dehydrogenase Cluster of Mycoplasma pneumoniae Are Surface-Displayed Proteins that Bind and Activate Human Plasminogen.
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