KCNMB3 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against partial recombinant human KCNMB3.
Immunogen
Recombinant protein corresponding to human KCNMB3.
Sequence
RLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with KCNMB3 polyclonal antibody (Cat # PAB30908) shows strong cytoplasmic positivity in granular pattern in glandular cells. -
Gene Info — KCNMB3
Entrez GeneID
27094Protein Accession#
Q9NPA1Gene Name
KCNMB3
Gene Alias
KCNMB2, KCNMBL
Gene Description
potassium large conductance calcium-activated channel, subfamily M beta member 3
Omim ID
605222Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq
Other Designations
calcium-activated potassium channel beta 3 subunit|large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit|potassium large conductance calcium-activated channel beta 3 subunit
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Interactomes
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Pathways
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Diseases
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