UPK3A polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human urinary bladder with UPK3A polyclonal antibody (Cat # PAB30900) shows strong membranous positivity in umbrella cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human UPK3A.
Immunogen
Recombinant protein corresponding to human UPK3A.
Sequence
QILNAYLVRVGANGTCLWDPNFQGLCNPPLSAATEYRFKYVLVNMSTGLVEDQTLWSDPIRTNQLTPYSTIDTWPGRRSGGMIVIT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human urinary bladder with UPK3A polyclonal antibody (Cat # PAB30900) shows strong membranous positivity in umbrella cells. -
Gene Info — UPK3A
Entrez GeneID
7380Protein Accession#
O75631Gene Name
UPK3A
Gene Alias
MGC119178, UPIII, UPIIIA, UPK3
Gene Description
uroplakin 3A
Omim ID
611559Gene Ontology
HyperlinkGene Summary
Uroplakins (UPK) are integral membrane proteins that form 2-dimensional crystalline arrays termed urothelial plaques that cover more than 90% of the apical urothelial surface. The asymmetric unit membrane (AUM) forms the apical plaques of urothelium and is believed to strengthen the urothelial apical surface and prevent the cells from rupturing during bladder distention. The 4 major conserved integral membrane proteins of the AUM are UPK1A (MIM 611557), UPK1B (MIM 602380), UPK2 (MIM 611558), and UPK3A.[supplied by OMIM
Other Designations
OTTHUMP00000028951|uroplakin III
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Interactome
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Disease
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