SNRPB polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SNRPB.
Immunogen
Recombinant protein corresponding to human SNRPB.
Sequence
TFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQ
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-50)
Western Blot (1:100-250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of human NTERA-2 cell.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lateral ventricle shows strong nuclear positivity in neuronal cells and glial cells. -
Gene Info — SNRPB
Entrez GeneID
6628Protein Accession#
P14678Gene Name
SNRPB
Gene Alias
COD, SNRPB1, SmB/SmB', snRNP-B
Gene Description
small nuclear ribonucleoprotein polypeptides B and B1
Omim ID
182282Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq
Other Designations
B polypeptide of Sm protein|OTTHUMP00000030012|OTTHUMP00000030013|Sm protein B/B'|small nuclear ribonucleoprotein polypeptide B|small nuclear ribonucleoprotein polypeptide B/B'|small nuclear ribonucleoprotein polypeptides B and B'
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Interactome
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Pathway
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Disease
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