RBX1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of human RT-4 cell.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum shows nuclear positivity in Purkinje cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human RBX1.
Immunogen
Recombinant protein corresponding to human RBX1.
Sequence
MAAAMDVDTPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEF
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
Western Blot (1:100-250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of human RT-4 cell.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum shows nuclear positivity in Purkinje cells. -
Gene Info — RBX1
Entrez GeneID
9978GeneBank Accession#
P62877Gene Name
RBX1
Gene Alias
BA554C12.1, MGC13357, MGC1481, RNF75, ROC1
Gene Description
ring-box 1
Omim ID
603814Gene Ontology
HyperlinkGene Summary
This gene encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over. [provided by RefSeq
Other Designations
OTTHUMP00000028983|RING box protein 1|RING finger protein|ZYP protein|regulator of cullins 1
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Interactome
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Pathway
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