PRPS1/PRPS2/PRPS3 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PRPS1/2/3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PRPS1/2/3.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Saturated Ammonium Sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse kidney tissue lysate with PRPS1/PRPS2/PRPS3 polyclonal antibody (Cat # PAB30838).Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of HeLa cell lysate with PRPS1/PRPS2/PRPS3 polyclonal antibody (Cat # PAB30838).Enzyme-linked Immunoabsorbent Assay
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Gene Info — PRPS1
Entrez GeneID
5631Protein Accession#
P60891Gene Name
PRPS1
Gene Alias
ARTS, CMTX5, KIAA0967, PPRibP, PRSI
Gene Description
phosphoribosyl pyrophosphate synthetase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000023807|dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1)
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Gene Info — PRPS2
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Gene Info — PRPS1L1
Entrez GeneID
221823Protein Accession#
P60891Gene Name
PRPS1L1
Gene Alias
PRPS1, PRPS3, PRPSL, PRS-III
Gene Description
phosphoribosyl pyrophosphate synthetase 1-like 1
Omim ID
611566Gene Ontology
HyperlinkGene Summary
This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq
Other Designations
phosphoribosylpyrophosphate synthetase subunit III|ribose-phosphate diphosphokinase catalytic chain III|ribose-phosphate pyrophosphokinase III
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Interactomes
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Pathways
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of plant hormones
- Biosynthesis of plant hormones
- Biosynthesis of plant hormones
- Metabolic pathways
- Metabolic pathways
- Metabolic pathways
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