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Last updated: 2017/7/23

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MYLK3 polyclonal antibody

  • Catalog # : PAB30836
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MYLK3.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to amino acids 40-69 at N-terminus of human MYLK3.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Saturated Ammonium Sulfate precipitation
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate) analysis of A-375 cell lysate with MYLK3 polyclonal antibody (Cat # PAB30836). Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human breast carcinoma with MYLK3 polyclonal antibody (Cat # PAB30836), followed by peroxidase-conjugated secondary antibody and DAB staining.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • MYLK3
  • Gene Alias:
  • MGC126319,MGC126320,MLCK,MLCK2,caMLCK
  • Gene Description:
  • myosin light chain kinase 3
  • Gene Summary:
  • Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM
  • Other Designations:
  • MLC kinase,cardiac-MyBP-C associated Ca/CaM kinase
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