CHGA polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human parathyroid (A) and human pancreas (B) with CHGA polyclonal antibody (Cat # PAB30815).
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant human CHGA.
Immunogen
Recombinant protein corresponding to full length human CHGA.
Host
Rabbit
Theoretical MW (kDa)
68-75
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human parathyroid (A) and human pancreas (B) with CHGA polyclonal antibody (Cat # PAB30815).Immunofluorescence
Flow Cytometry
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Gene Info — CHGA
Entrez GeneID
1113Protein Accession#
P10645Gene Name
CHGA
Gene Alias
CGA
Gene Description
chromogranin A (parathyroid secretory protein 1)
Omim ID
118910Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq
Other Designations
betagranin (N-terminal fragment of chromogranin A)|chromogranin A|parathyroid secretory protein 1
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Interactome
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Disease
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Publication Reference
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Distribution of chromogranin A and secretogranin I (chromogranin B) in neuroendocrine cells and tumors.
Lloyd RV, Cano M, Rosa P, Hille A, Huttner WB.
The American Journal of Pathology 1988 Feb; 130(2):296.
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The primary structure of human chromogranin A and pancreastatin.
Konecki DS, Benedum UM, Gerdes HH, Huttner WB.
The Journal of Biological Chemistry 1987 Dec; 262(35):17026.
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Distribution of chromogranin A and secretogranin I (chromogranin B) in neuroendocrine cells and tumors.
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