DUSP16 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human DUSP16.
Immunogen
Recombinant protein corresponding to human DUSP16.
Sequence
KSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with DUSP16 polyclonal antibody (Cat # PAB30808) shows strong cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of U-2 OS with DUSP16 polyclonal antibody (Cat # PAB30808) (Green) shows positivity in nucleus but excluded from the nucleoli. -
Gene Info — DUSP16
Entrez GeneID
80824Protein Accession#
Q9BY84Gene Name
DUSP16
Gene Alias
KIAA1700, MGC129701, MGC129702, MKP-7, MKP7
Gene Description
dual specificity phosphatase 16
Omim ID
607175Gene Ontology
HyperlinkGene Summary
The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM
Other Designations
MAPK phosphatase-7
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Interactome
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Disease
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