SYNE1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skeletal muscle with SYNE1 polyclonal antibody (Cat # PAB30804) shows strong cytoplasmic and nuclear membranous positivity in myocytes.
Immunofluorescence
Immunofluorescent staining of U-251 MG with SYNE1 polyclonal antibody (Cat # PAB30804) (Green) shows positivity in nuclear membrane and nucleus but excluded from the nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SYNE1.
Immunogen
Recombinant protein corresponding to human SYNE1.
Sequence
SRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWEL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skeletal muscle with SYNE1 polyclonal antibody (Cat # PAB30804) shows strong cytoplasmic and nuclear membranous positivity in myocytes.Immunofluorescence
Immunofluorescent staining of U-251 MG with SYNE1 polyclonal antibody (Cat # PAB30804) (Green) shows positivity in nuclear membrane and nucleus but excluded from the nucleoli. -
Gene Info — SYNE1
Entrez GeneID
23345Protein Accession#
Q8NF91Gene Name
SYNE1
Gene Alias
8B, CPG2, DKFZp781J13156, FLJ30878, FLJ41140, KIAA0796, KIAA1262, KIAA1756, MYNE1, SCAR8
Gene Description
spectrin repeat containing, nuclear envelope 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000017437|OTTHUMP00000017438|enaptin|nesprin 1|nuclear envelope spectrin repeat protein 1|synaptic nuclei expressed gene 1
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Interactome
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Disease
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